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Population genetics


Semesterangivelse: Forårs kursus Kurset udbydes i blok 3 Kurset udbydes i skemagruppe C Kurset giver 7,5 ETCS point

 


Udgave: Forår 2013 NAT
ECTS points: 7,5
Point: 7,5
Blokstruktur: 3. blok
Skemagruppe: C
Institutter: Department of Biology
Uddannelsesdel: Kandidat niveau
Kontaktpersoner: Hans R. Siegismund, Bioinformatics Centre, phone 35 32 13 39, email: hsiegismund@bio.ku.dk
Andre undervisere: Søren Rosendahl
Skema- oplysninger:  Vis skema for kurset
Samlet oversigt over tid og sted for alle kurser inden for Lektionsplan for Det Naturvidenskabelige Fakultet Forår 2013 NAT
Undervisnings- form: Lectures, seminars, group discussions, computer workshops, and student presentations of original research papers.
Formål: The amount of molecular genetic data (especially nucleotide sequences) has increased tremendously in recent years and is expected to explode as the next generation sequencing methods become standard tools. This has implications for a wide spectrum of biological disciplines spanning conservation genetics, molecular ecology, molecular medicine, genome research and evolutionary biology. The purpose of the course is to provide the students with knowledge about the principles of population genetics phylogenetics and their applications in the diverse areas mentioned above. In addition, the course will train the students to choose suitable methods to analyze molecular genetic data.
Indhold:
  • Natural selection
  • Genetic drift and inbreeding
  • The neutral theory and molecular population genetics
  • Population structure
  • Evolutionary quantitative genetics
  • Phylogenetic inference (using distance, parsimony, maximum likelihood, and Bayesian methods)
  • Population genomics
  • Human population genetics
  • Applied aspects; depending on the participants’ interests
  • Målbeskrivelse:
    By completing the course the student can:
  • explain basic population genetic and phylogenetic principles
  • discuss, put into perspective, and criticize original research papers in population genetics and phylogenetics
  • choose the most suitable molecular methods to analyze a particular hypothesis
  • choose the most suitable analytical tools to analyze molecular genetic data
  • perform statistical analyses of population genetic and phylogenetic data, present the results, and put them into perspective
  • Lærebøger: Compulsory: Hartl, D.L & A.G Clark, 2007, Principles of Population Genetics, 4th edition, Sinauer Associates, Inc.
    For those who need a hands-on introduction to phylogenetics, we recommend Hall, B.G. 2011, Phylogenetic Trees Made Easy: A How-To Manual, 4th edition, Sinauer Associates, Inc.
    Original papers and lecture notes.
    Tilmelding: Registration at KUnet 15 November - 1 December.
    Faglige forudsætninger: Knowledge within biology and molecular biology disciplines is recommended.
    Eksamensform: The students will carry out a population genetic project in groups and hand-in a joint paper presenting the project. This paper is presented individually at an oral examination and is graded following the 7 scale with the participation of an external examiner (censor).
    Re-examination: Same as ordinary exam.
    Eksamen: Aflevering af opgave d. 3. april 2013 og mundtlig prøve d. 10. april 2013.
    Reeksamen: Aflevering af opgave d. 24. juni 2013 og mundtlig prøve d. 26. juni 2013.
    Kursus hjemmeside:
    Bemærkninger: The course is part of the qualification profiles Ecology and Evolution and Microbiology. For all courses of the qualification profiles, see Course Portal for Department of Biology.
    Teaching language will be English, unless all participants are Danish speaking.
    Undervisnings- sprog: Engelsk
    Sidst redigeret: 26/10-2012



    Københavns Universitet