Hjertefysiologi (Cardiac Physiology) (SUND)


Semesterangivelse: Efterårs kursus Kurset udbydes i blok 2 Kurset udbydes i skemagruppe B Kurset giver 7,5 ETCS point

 


Udgave: Efterår 2012 NAT
Point: 7,5
Blokstruktur: 2. blok
Skemagruppe: B
Uddannelsesdel: Kandidat niveau
Kontaktpersoner: Thomas Jespersen, tlf. 2480 5190, email: thojes@sund.ku.dk; Morten Schak Nielsen, email; schak@sund.ku.dk; tlf. 3532 7427
Undervisnings- form: 20 lectures, 10 seminars, and 2 practical exercises. The seminars include student presentations of original articles. Following this, students must write a literature based essay (5 pages pr. person) on a given topic related to the course lectures and papers.
Indhold: Basic concepts of cardiac physiology: The genesis and propagation of the cardiac action potential; the molecular components underlying the different cardiac ionic currents; regulation of these components in health and disease; excitation-contraction coupling and cardiac output; ECG; human cardiac diseases, including arrhythmias and heart failure; pharmacotherapy; animal models; drug discovery and cardiovascular safety. The practical exercises will provide the student with hands on experience concerning cardiac experimentation in respect to fully functional explanted hearts and multicellular cardiac tissue strips.
Målbeskrivelse: To offer students a thorough understanding of cardiac physiology and pathophysiology. Students will gain a detailed perception of pacemaking and of action potential propagation and termination in the different parts of the heart. The delicate ionic balance responsible for adjusting the action potential morphology, as well as several of the parameters influencing this balance, including parasympathetic and sympathetic stimulation, will become clear. Following this course, students will understand the link between calcium handling, excitation-contraction coupling, and pumping efficiency. The causal connection between molecular regulation, protein function, and physiological performance will be evident. Finally, an outline of the patho-physiological and -molecular mechanisms underlying several different cardiac diseases will be known after completion of this course.
Lærebøger: Levick; ”An introduction to cardiovascular physiology”, review and original articles, lecture and exercise notes.
Eksamensform: The first part of the oral examination is a discussion of the literature based essay. The second part consists of questions based on the above-mentioned curriculum. The exam lasts for 25 minutes in total. The essay and the oral examination will be graded jointly under participation of an internal censor.
Re-examination: Same.
Examination rules for the Faculty of Health Sciences
In order to be eligible for re-examination at the Faculty’s courses, you must have made an attempt at the ordinary exam. An attempt is defined as a personal appearance, where you hand in an empty exam paper/assignment, or by presenting a signed doctor’s certificate no later than 3 days after the exam. That means that it is not possible to sign up for a re-examination if you have not made an attempt at the ordinary exam.
Kursus hjemmeside:
Bemærkninger: The course takes place in the Panum Building.
Undervisnings- sprog: Engelsk
Sidst redigeret: 25/4-2012



Københavns Universitet