|
| Udgave: |
Efterår 2011 NAT |
| ECTS points: |
7,5 |
| Punkter: |
7,5 |
| Point: |
7,5 |
| Blokstruktur: |
1. blok |
| Skemagruppe: |
C |
Semester: |
Efterår 2011 |
| Varighed: |
4 uger |
| Omfang: |
Classroom teaching 12 hours, group discussions 11 hours and laboratory exercises 12 hours |
| Institutter: |
Department of Neurobiology and Molecular Phamacology, Faculty og Health Sciences |
| Uddannelsesdel: |
Bachelor niveau |
| Kontaktpersoner: |
Jean-Francois Perrier, email: perrier@sund.ku.dk, tel.: +45 35327447 or Jørn Hounsgaard, email: j.hounsgaard@sund.ku.fk, tel.: +45 3532 7559 |
| Skema- oplysninger: |
Se Syllabus |
| Undervisnings- periode: |
Uge 36-39 |
| Undervisnings- form: |
Classroom teaching 12 hours, group discussions 11 hours and laboratory exercises 12 hours. |
| Formål: |
The goal of the course is to give the students an overview of methods used to study functions of the central nervous system. We will provide an insight in signaling mechanisms in neurons and networks of neurons by describing how the molecular mechanisms of electrical and chemical signalilng are adapted to serve synaptic transmission, synaptic integration and nerve impulse generation. We will use the spinal motor neuronal network as a functional example. The Course will illustrate how experiments led to textbook knowledge and provide insight in experimental procedures, techniques and preparations. |
| Indhold: |
The course includes theoretical and practical elements. The theory will focus on cellular and molecular properties of neurons and their implications in physiological functions. In addition to basic subjects, the course will highlight a) The role of the non-linear postsynaptic properties provided by voltage sensitive ion channels in dendrites. b) Modulation of these properties by G-protein coupled receptors. c)Functional specialization of cell types in particular brain regions and d)Signaling networks in particular brain regions with a focus on spinal neuronal networks. The Practical part will include demonstrations of preparations of nerve tissues in vitro, recording electrical activity from neurons with intracellular and patch clamp techniques and recording signaling in neurons during functional network activity. Each student will have the opportunity to record from living neurons and to characterize some of the transmembrane currents responsible for firing properties by means of electrophysiological and pharmacological tools. |
| Lærebøger: |
Cellular and Molecular Neurophysiology, third edition. Constance Hammond Academic Press (ISBN 0123741270) |
| Tilmelding: |
Through Punkt KU. |
| Faglige forudsætninger: |
Open to students in Molecular Biomedicine, Biochemestry and Biologi that have passed relevant first and second year courses. |
| Eksamensform: |
An oral presentation of one article on a self chosen subject within the course combined with a discussion, with participation of an internal or external examiner. The practical laboratory course must be approved to participate in the examination.
Examination rules for the Faculty of Health Sciences
In order to be eligible for re-examination at the Faculty’s courses, you must have made an attempt at the ordinary exam. An attempt is defined as a personal appearance, where you hand in an empty exam paper/assignment, or by presenting a signed doctor’s certificate no later than 3 days after the exam. That means that it is not possible to sign up for a re-examination if you have not made an attempt at the ordinary exam.
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| Kursus hjemmeside: |
 |
| Sidst redigeret: |
23/8-2011 |