|
Udgave: |
Efterår 2012 NAT |
Point: |
7,5 |
Blokstruktur: |
2. blok |
Skemagruppe: |
A |
Fagområde: |
fys |
Institutter: |
Niels Bohr Institute |
Uddannelsesdel: |
Kandidat niveau |
Kontaktpersoner: |
Thomas Heimburg, tel: 35 32 53 89, office: Kc9, email: theimbu@nbi.dk. |
Skema- oplysninger: |
Vis skema for kurset Samlet oversigt over tid og sted for alle kurser inden for Lektionsplan for Det Naturvidenskabelige Fakultet Efterår 2012 NAT |
Undervisnings- periode: |
19. november 2012 til 27. januar 2013 |
Undervisnings- form: |
6 hours of Lectures, 1 hour of excercises. |
Formål: |
This course goes beyond standard thermodynamics and introduces modern concepts of
non-equilibrium process. This will be described the phenomena of life.
|
Indhold: |
Biological organisms are open thermodynamic systems with metabolism (food and
breathing). Most processes
are not in equilibrium. Thermodynamic forces and fluxes
drive reaction under consumption of energy and
dissipation of entropy. Such
processes are irreversible. The understanding of non-equilibrium processes
is
important to analyze molecular reactions, protein function and metabolism in
biology. This course introduces
into the thermodynamics of irreversible processes
and into the application of these concepts to elementary
biological reactions (e.g.
channel activities). Under certain conditions stable fluxes (stationary states)
develop, or dissipative stuctures can form. Criteria for defining such states are
formulated. Ultimately one arrives at the formation of chemical oszillations and
biological clocks. In reproducing organisms, such oszillations can lead
to
reproductive cycles (hypercycles) that compete with other organisms. Fitness is a
consequence of reproductive
speed, error and death rate. Important key topics of
this course are information, self reproduction, self
organisation and
evolution. |
Målbeskrivelse: |
After this course students should be able to:
- Handle the entropy as a potential
- Derive cycle kinetics and its application to ion pumps
- Work with thermodynamic forces and fluxes
- Work with Onsager's equations, and understand the concept of microscopic
reversibility
- Understand the concept of 'information' and its relationship to entropy.
- Describe oscillatory reactions
- Derive the equation for evolution
- Understand the concepts of hypercycles, quasispecies, mutation
12 is given for a presentation where the student displays an independent ability of
deriving and working with the concepts described in the course goals
2 is given for an insecure presentation where the student can only reproduce a
minimum of what has been described under course goals. |
Lærebøger: |
There will be handouts that are sufficient to understand the course. Recommended is
the reading of: "Modern Thermodynamics: From Heat Engines to Dissipative Structures
(Paperback) by D. Kondepudi and I. Prigogine". |
Tilmelding: |
Foregår på selvbetjeningen d. 15.maj - 1. juni |
Faglige forudsætninger: |
Physics bachelor, Chemists and Biologists with previous training in thermodynamics. |
Eksamensform: |
Oral exam for 30 minutes. The student gives a presentation about a subject from the course for 15 minutes without notes and further examination for another 10 minutes. Intern censor. Graded according to the 7 step scale. Reexam the same as the ordinary. |
Eksamen: |
Mundtlig prøve den 24. januar 2013.
Reeksamen: Mundtlig prøve den 18. april 2013. |
Kursus hjemmeside: |
 |
Kursus hjemmeside: |
http://membranes.nbi.dk/courses/nonequilibrium.html |
Undervisnings- sprog: |
Kun engelsk
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Sidst redigeret: |
26/4-2012 |